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Here we targeted single-element transcranial focused ultrasound to the thalamus, a deep brain region shown above. tFUS is uniquely able to modulate deep brain regions due to its high spatial resolution. In the present study, tFUS was targeted at unilateral thalamus and was shown to inhibit the amplitude of the P14 SEP as compared to sham. These results were accompanied by alpha and beta power attenuation as well as time‐locked gamma power inhibition. Furthermore, participants performed significantly worse than chance on a discrimination task during tFUS stimulation. Click here for the full article.